from PhysioNet, the research resource for complex physiologic signals


Sudden Cardiac Death Holter Database

This database is described in

Greenwald SD. Development and analysis of a ventricular fibrillation detector. M.S. thesis, MIT Dept. of Electrical Engineering and Computer Science, 1986.

Please cite this publication when referencing this material, and also include the standard citation for PhysioNet:

Goldberger AL, Amaral LAN, Glass L, Hausdorff JM, Ivanov PCh, Mark RG, Mietus JE, Moody GB, Peng C-K, Stanley HE. PhysioBank, PhysioToolkit, and PhysioNet: Components of a New Research Resource for Complex Physiologic Signals. Circulation 101(23):e215-e220 [Circulation Electronic Pages; http://circ.ahajournals.org/cgi/content/full/101/23/e215]; 2000 (June 13).

An estimated 400,000 Americans, and millions more worldwide, die suddenly each year. These events are most often initiated with a sustained ventricular tachyarrhythmia, including ventricular tachycardia (monomorphic or polymorphic), ventricular flutter, or ventricular fibrillation, with a smaller percentage related to a primary bradyarrhythmia. Sudden cardiac death syndrome may be due to a wide variety of different electrical and mechanical substrates, including acute myocardial infarction, chronic coronary disease with prior myocardial infarction(s), cardiomyopathies, myocarditis, valvular heart disease, right ventricular dysplasia, the long Q-T syndrome (acquired or congenital), Wolff-Parkinson-White pre-excitation, the Brugada syndrome, drug toxicity (e.g., proarrhythmic effects of cardioactive drugs; epinephrine, cocaine, and related stimulants), and so forth. Moreover, some individuals have no demonstrable electrical or mechanical predisposition.

PhysioNet has inaugurated a Sudden Cardiac Death Database to support research and to stimulate progress in this important area of electrophysiology. We initiate this database with 23 complete Holter recordings (originally collected by Scott Greenwald while he was at MIT), from which half-hour excerpts have been available to researchers since 1989 as the MIT-BIH Malignant Ventricular Arrhythmia Database. The database currently includes 18 patients with underlying sinus rhythm (4 with intermittent pacing), 1 who was continuously paced, and 4 with atrial fibrillation. All patients had a sustained ventricular tachyarrhythmia, and most had an actual cardiac arrest.

These recordings were mainly obtained in the 1980s in Boston area hospitals, and were later compiled as part of a study of ventricular arrhythmias. Because of the retrospective nature of this collection, there are important limitations. Patient information is limited, and sometimes completely unavailable, including data regarding drug regimens and drug dosages. Further, these cases may not be representative of spontaneous episodes of sudden death in what is likely a very heterogenous group of subjects. Despite these shortcomings, these unique recordings may provide important clues to the pathogenesis of sudden death syndrome.

This is a small collection of an important type of data. The task of annotating this database is particularly difficult because of the complexity of the included cardiac rhythms. We invite the community to help us make this collection larger, more representative, and more useful, and to annotate it more thoroughly and rigorously. We welcome contributions of additional data from other investigators who have access to similar records. We also invite interested researchers to review and revise the annotation files provided for these recordings; if you are interested in participating in this effort, please write for additional information. We will gratefully acknowledge all contributions.

References


ECG data and beat annotations

A list in plain text form of the names of the records in this database can be found here.

Signals Header Unaudited
Annotations
Audited
Annotations
Signal
Duration
VF Onset
Time (elapsed)
View
Waveform
30.dat 30.hea 30.ari 30.atr 24:33:17 07:54:33 30-waveform
31.dat 31.hea 31.ari 31.atr 13:58:40 13:42:24 31-waveform
32.dat 32.hea 32.ari 32.atr 24:20:00 16:45:18 32-waveform
33.dat 33.hea 33.ari   24:33:00 04:46:19 33-waveform
34.dat 34.hea 34.ari 34.atr 07:05:20 06:35:44 34-waveform
35.dat 35.hea 35.ari 35.atr 24:52:00 24:34:56 35-waveform
36.dat 36.hea 36.ari 36.atr 20:21:20 18:59:01 36-waveform
37.dat 37.hea 37.ari   25:08:00 01:31:13 37-waveform
38.dat 38.hea 38.ari   18:18:25 08:01:54 38-waveform
39.dat 39.hea 39.ari   05:47:00 04:37:51 39-waveform
40.dat 40.hea 40.ari   24:53:00 (paced, no VF) 40-waveform
41.dat 41.hea 41.ari 41.atr 03:56:00 02:59:24 41-waveform
42.dat 42.hea 42.ari   25:08:10 (no VF) 42-waveform
43.dat 43.hea 43.ari   23:07:50 15:37:11 43-waveform
44.dat 44.hea 44.ari   23:20:00 19:38:45 44-waveform
45.dat 45.hea 45.ari 45.atr 24:09:20 18:09:17 45-waveform
46.dat 46.hea 46.ari 46.atr 04:15:10 03:41:47 46-waveform
47.dat 47.hea 47.ari   23:35:50 06:13:01 47-waveform
48.dat 48.hea 48.ari   24:36:15 02:29:40 48-waveform
49.dat 49.hea 49.ari 49.atr 25:01:40 (paced, no VF) 49-waveform
50.dat 50.hea 50.ari   23:07:38 11:45:43 50-waveform
51.dat 51.hea 51.ari 51.atr 25:08:30 22:58:23 51-waveform
52.dat 52.hea 52.ari 52.atr 07:31:05 02:32:40 52-waveform

Clinical information

Subject # Gender Age History Medication Underlying Cardiac Rhythm
30 Male 43   Unknown   Unknown   Sinus
31 Female 72   Heart failure   digoxin; quinidine gluconate   Sinus
32 Unknown 62   Coronary bypass grafting; history of arrhythmia   Procan SR; beta-blocker   Sinus with intermittent demand ventricular pacing; CPR at time of cardiac arrest  
33 Female 30   Unknown   Unknown   Sinus
34 Male 34   Unknown   Unknown   Sinus
35 Female 72   Mitral valve replacement   digoxin   Atrial fibrillation
36 Male 75   Cardiac surgery   digoxin; quinidine   Atrial fibrillation
37 Female 89   Unknown   Unknown   Atrial fibrillation
38 Unknown Unknown   Unknown   Unknown   Sinus
39 Male 66   Acute myelogenous leukemia   digoxin; quinidine   Sinus
40 Male 79   Unknown   Unknown   Paced
41 Male Unknown   Unknown   Unknown   Sinus
42 Male 17   Hypertrophic cardiomyopathy; positive family history of sudden death   Unknown   Sinus
43 Male 35   Coronary artery disease   Unknown   Intermittent ventricular pacing
44 Male Unknown   Unknown   Unknown   Sinus
45 Male 68   History of ventricular ectopy   digoxin; quinidine gluconate   Sinus
46 Female Unknown   Unknown   Unknown   Sinus
47 Male 34   Unknown   Unknown   Sinus
48 Male 80   Unknown   Unknown   Sinus
49 Male 73   Coronary artery s/p myocardial infarction; history of ventricular tachycardia   Unknown   Sinus with intermittent pacing
50 Female 68   Coronary artery bypass graft; mitral valve replacement   digoxin; quinidine; propranolol; potassium; diuretics   Atrial fibrillation
51 Female 67   Unknown   Unknown   Sinus with intermittent pacing
52 Female 82   Heart failure   None listed   Sinus